| Pair Name | Bufalin, Vorinostat | ||
| Phytochemical Name | Bufalin (PubChem CID: 9547215 ) | ||
| Anticancer drug Name | Vorinostat (PubChem CID: 5311 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Bufalin, Vorinostat | |||
| Disease Info | [ICD-11: 2A00-2F9Z] | Solid tumour or cancer | Investigative | |
| Biological Phenomena | Induction-->Apoptosis | |||
| Gene Regulation | Up-regulation | Activity | AKT1 | hsa207 |
| Down-regulation | Expression | BCL2 | hsa596 | |
| In Vitro Model | MDA-MB-231 | Breast adenocarcinoma | Homo sapiens (Human) | CVCL_0062 |
| A-549 | Lung adenocarcinoma | Homo sapiens (Human) | CVCL_0023 | |
| Result | These accumulating data might guide development of new breast and lung cancer therapies. | |||
| No. | Title | Href |
|---|---|---|
| 1 | Inhibition of SRC-3 enhances sensitivity of human cancer cells to histone deacetylase inhibitorsInhibition of SRC-3 enhances sensitivity of human cancer cells to histone deacetylase inhibitors. Biochem Biophys Res Commun. 2016 Sep 9;478(1):227-233. doi: 10.1016/j.bbrc.2016.07.063. | Click |
